Overview

Cell-free DNA (cfDNA) testing, also referred to as Non-invasive prenatal testing (NIPT) has dramatically changed prenatal care. It allows for highly accurate screening for fetal trisomies in twin pregnancies and its performance is similar to that
reported in singleton pregnancies and is superior to that of the first-trimester combined test or second-trimester biochemical testing.

Twin pregnancies pose unique challenges for clinicians, including special considerations in prenatal screening for aneuploidy. Here in this workshop we will present evidence supporting the use of cfDNA testing in twin pregnancies, which has grown substantially in recent years. We will also present the clinical implementation of cell-free DNA testing, where questions arise about considerations in special populations such as IVF, PGT, obesity and others. 

Learning objectives

• Clinical evidence in twin pregnancies
  
• Understanding the importance of measuring, incorporating and reporting fetal fraction in cfDNA testing in the clinical context
  
• Shedding the lights on special populations such as IVF, PGT, obesity and others upon cfDNA testing
  

Target audience

• Obstetricians
• Gynecologists
• Prenatal medicine specialists
• Laboratory Doctors

Presenter

Dr. Samina Dornan, Consultant OBGYN, Sub specialist and lead Maternal & Fetal Medicine King’s College Hospital London UAE

Dr Samina M Dornan MD, FRCOG, is an attending high-risk obstetrician and sub specialist in Maternal Fetal Medicine at King’s College Hospital London, UAE. She is also the Head of the said department.

Her areas of expertise include: prenatal counseling, Fetal Growth Restriction, prenatal diagnosis and fetal therapy, fetal genetic disorders, including trisomies and fetal structural abnormalities including congenital diaphragmatic hernia. She also specializes and has extensively published in Complex twin pregnancies, especially monochorionic, with the fetal and placental biochemical responses involved in twin-twin transfusion syndrome. Her expertise also includes general obstetrics and gynaecology, along with managing high-risk mothers, their pregnancies and fetuses.